Symposium on Nanoparticle-based technologies for cell tracking.
1 & 2 July 2013
For all practical details, invited speakers, registration, etc, see the symposium website.
There is a growing interest in techniques that allow the in vivo imaging of cells that have been transplanted into animals and humans, which stems from the need for a better understanding of cellular fate in biological processes. Cancer research and cell based therapies are two fields of research that would greatly benefit from real-time non-invasivein vivo cell imaging, allowing the possibility to follow cell migration, distribution and engraftment following transplantation. This would allow the determination of the fate and metastatic potential of cancer cells in animal models, as well as the tracking of cells employed in regenerative therapies (stem cells) or immunotherapy (immune effector cells).
This symposium will be a forum for discussion on the latest research and challenges concerning imaging technologies that make use of nanoparticles as contrast agents for in vivo cell imaging.
The following topics will be covered:
- Synthesis of nanoparticles that can act as contrast agents (e.g. magnetic, fluorescent and radioactive nanoparticles)
- Functionalisation of nanoparticles for improved labelling, stability, biocompatibility or contrast
- Cell labelling methods
- Nanoparticle fate upon endocytosis (organelle delivery, cytotoxicity, metabolisation)
- Imaging technologies and methods for contrast enhancement
- Pre-clinical and clinical studies.
Prof. Matthew Rosseinsky, Prof. David Fernig, Dr. Patricia Murray, Dr. Raphaël Lévy, Dr. Dave Adams, Dr. Solène Cauët, Dr. Lara Bogard, Dr. Arthur Taylor (University of Liverpool) and Prof. Stephen Williams (University of Manchester).