Thanks to the organizers (Kimberly Hamad-Schifferli, MIT, Clemens Burda, Case Western Reserve University, and Wolfgang Parak Univ. Marburg, Germany) of the symposium “Protein-Nanomaterial interfaces and protein coronas@ physical properties, biocompatibility and biological impact*” for inviting me as one of their speakers. Abstract submission is now open. I have attended a couple of MRS national meetings, but for some reasons, I have never been to an ACS national meeting before. I am very much looking forward to this. Maybe leave a comment (or tweet or email) if you would like to meet up?
* symposium description:
The synergistic combination of nanotechnology and biology has resulted in numerous innovative approaches for therapy and biology. One of the biggest issues for effective use of nanoparticles in biology is the interface between the nanomaterial and its biological environment. When nanoparticles are introduced to biological fluids, the proteins and other species present non-specifically adsorb to their surfaces, forming a “protein corona.” The corona can block the surface of the nanoparticle, cause undesired side effects in targeting, biocompatibility, biodistribution, and other biological consequences. Probing the nanomaterial-protein interface poses unique challenges, as interactions are weak and constantly evolving. This symposium will focus on the interface of nanomaterials with biomolecules, cells, biological fluids, properties of protein coronas, protein- and DNA-nanoparticle interactions, as well as the impact of the nanomaterial-biological interface on biocompatibility, biodistribution, in vitro and in vivo toxicity.