£1M to improve imaging of biomolecules and nanoparticles in live cells

We have been awarded £1 million to advance imaging techniques to improve understanding of the processes that occur inside living cells.

The award is part of a £25.5 million investment into microscope technology from the Medical Research Council (MRC), the Biotechnology and Biological Sciences Research Council (BBSRC), and the Engineering and Physical Sciences Research Council (EPSRC). [check the nice image gallery here]

With the £1M, the Centre for Cell Imaging will acquire new equipment and recruit new staff to support work by users from across the University, the NHS and local biotech industries.

Dr Violaine Sée and Dr Daimark Bennett, who are Co-Directors of the facility, say:

The Centre for Cell Imaging is used by dozens of research groups across the University and beyond supporting research into many important scientific and medical fields such as cancer, pancreatitis, aging, infection and the development of nanomedicines. Thanks to this grant, researchers will benefit from the latest imaging technologies to investigate cellular events at the molecular level as they unfold in real-time.

The Centre for Cell Imaging will develop unique capabilities for the determination of oxygen concentration inside living cells. This is critical for the understanding of resistance of malignant cells to anticancer drugs, as well as many other biological processes.  The Centre will also upgrade one of its photothermal microscopes for the imaging of gold nanoparticles with nanometre resolution.

Raphaël Lévy, who is leading the next generation microscopy grant, comments:

This upgrade will make it easier for external users to benefit from this powerful technique. We have already had expression of interest from collaborators in India, Europe and USA: this new development will help the nanoscience community to better understand the dynamic interaction of man-made nanoparticles with living cells




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