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	<title>Rapha-z-lab</title>
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	<description>The blog of Raphaël Lévy's lab at the University of Liverpool</description>
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		<item>
		<title>Theme issue of Advanced Drug Delivery Reviews</title>
		<link>http://raphazlab.wordpress.com/2012/01/13/theme-issue-of-advanced-drug-delivery-reviews/</link>
		<comments>http://raphazlab.wordpress.com/2012/01/13/theme-issue-of-advanced-drug-delivery-reviews/#comments</comments>
		<pubDate>Fri, 13 Jan 2012 21:44:13 +0000</pubDate>
		<dc:creator>Raphaël Lévy</dc:creator>
				<category><![CDATA[Editor]]></category>
		<category><![CDATA[New publication]]></category>
		<category><![CDATA[bionano]]></category>
		<category><![CDATA[cells]]></category>
		<category><![CDATA[delivery]]></category>
		<category><![CDATA[endosome]]></category>
		<category><![CDATA[fluorescence]]></category>
		<category><![CDATA[Functional Biointerfaces]]></category>
		<category><![CDATA[intracellular delivery]]></category>
		<category><![CDATA[materials]]></category>
		<category><![CDATA[nanoparticle]]></category>
		<category><![CDATA[non-specific interactions]]></category>
		<category><![CDATA[peptide]]></category>
		<category><![CDATA[quantum dots]]></category>
		<category><![CDATA[theme issue]]></category>
		<category><![CDATA[toxicity]]></category>

		<guid isPermaLink="false">http://raphazlab.wordpress.com/?p=688</guid>
		<description><![CDATA[Together with Mathias Brust, we have co-edited a theme issue of Advanced Drug Delivery Reviews which include the following six articles: Toxicology of nanoparticles, Andreas Elsaesser, C. Vyvyan Howard Luminescent quantum dots as platforms for probing in vitro and in vivo biological processes, Hedi Mattoussi, Goutam Palui, Hyon Bin Na Quantum dots to tail single [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=raphazlab.wordpress.com&amp;blog=4635881&amp;post=688&amp;subd=raphazlab&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p>Together with Mathias Brust, we have co-edited a theme issue of Advanced Drug Delivery Reviews which include the following six articles:</p>
<ul>
<li><a title="Howard Review" href="http://dx.doi.org/10.1016/j.addr.2011.09.001" target="_blank">Toxicology of nanoparticles</a>, Andreas Elsaesser, C. Vyvyan Howard</li>
<li><a title="Review Mattoussi" href="http://dx.doi.org/10.1016/j.addr.2011.09.011" target="_blank">Luminescent quantum dots as platforms for probing in vitro and in vivo biological processes</a>, Hedi Mattoussi, Goutam Palui, Hyon Bin Na</li>
<li><a title="Review Cappello" href="http://dx.doi.org/10.1016/j.addr.2011.06.004" target="_blank">Quantum dots to tail single bio-molecules inside living cells</a>, Paolo Pierobon, Giovanni Cappello</li>
<li><a title="Coll Review" href="dx.doi.org/10.1016/j.addr.2011.09.009" target="_blank">Physico-chemical parameters that govern nanoparticles fate also dictate rules for their molecular evolution</a>, Sandrine Dufort, Lucie Sancey, Jean-Luc Coll</li>
<li><a title="Murphy Review" href="http://dx.doi.org/10.1016/j.addr.2011.03.005" target="_blank">Gold nanorods: Their potential for photothermal therapeutics and drug delivery, tempered by the complexity of their biological interactions</a>, Alaaldin M. Alkilany, Lucas B. Thompson, Stefano P. Boulos, Patrick N. Sisco, Catherine J. Murphy</li>
<li><a title="Rotello Review" href="dx.doi.org/10.1016/j.addr.2011.08.006" target="_blank">Monolayer coated gold nanoparticles for delivery applications</a>, Subinoy Rana, Avinash Bajaj, Rubul Mout, Vincent M. Rotello</li>
</ul>
<p>and, of course, <a title="Editorial Brust Levy" href="http://dx.doi.org/10.1016/j.addr.2011.12.012" target="_blank">our Editorial</a>, which starts as follows,</p>
<blockquote><p>Biological systems, albeit magnificently well organized on the nanometer scale, do not contain nanoparticles, least those of metals or semiconductors. This should be sufficient reason to question the need to dedicate a themed issue of <em>Advanced Drug Delivery Reviews</em> to “Biological Interactions of Nanoparticles”. What is new and needs to be highlighted?</p></blockquote>
<p>That is the question&#8230; for the answer, you will have to read the Editoral and the articles!</p>
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		<title>Amyloid-Derived Peptide Forms Self-Assembled Monolayer</title>
		<link>http://raphazlab.wordpress.com/2012/01/13/amyloid-derived-peptide-forms-self-assembled-monolayer/</link>
		<comments>http://raphazlab.wordpress.com/2012/01/13/amyloid-derived-peptide-forms-self-assembled-monolayer/#comments</comments>
		<pubDate>Fri, 13 Jan 2012 21:18:17 +0000</pubDate>
		<dc:creator>Raphaël Lévy</dc:creator>
				<category><![CDATA[New publication]]></category>
		<category><![CDATA[structural nanotechnology]]></category>
		<category><![CDATA[Amyloid]]></category>
		<category><![CDATA[Chris]]></category>
		<category><![CDATA[fibres]]></category>
		<category><![CDATA[Functional Biointerfaces]]></category>
		<category><![CDATA[nanoparticle]]></category>
		<category><![CDATA[peptide]]></category>
		<category><![CDATA[self-organization]]></category>

		<guid isPermaLink="false">http://raphazlab.wordpress.com/?p=695</guid>
		<description><![CDATA[on Gold Nanoparticle with a Curvature-Dependent β-Sheet Structure&#8230; That is the title of our ms just accepted in ACS Nano; congratulations to Chris, first author, and thanks to Martin Volk and David Middleton for their invaluable help with the use of FTIR and solid state NMR to elucidate the structure of peptides at the surface [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=raphazlab.wordpress.com&amp;blog=4635881&amp;post=695&amp;subd=raphazlab&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p><strong><a title="ACS Nano Shaw et al" href="http://pubs.acs.org/doi/abs/10.1021/nn204214x" target="_blank">on Gold Nanoparticle with a Curvature-Dependent β-Sheet Structure</a>&#8230;</strong></p>
<p>That is the title of our ms just accepted in ACS Nano; congratulations to Chris, first author, and thanks to Martin Volk and David Middleton for their invaluable help with the use of FTIR and solid state NMR to elucidate the structure of peptides at the surface of gold nanoparticles.</p>
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		<title>Dr Shaw</title>
		<link>http://raphazlab.wordpress.com/2012/01/13/dr-shaw/</link>
		<comments>http://raphazlab.wordpress.com/2012/01/13/dr-shaw/#comments</comments>
		<pubDate>Fri, 13 Jan 2012 21:10:43 +0000</pubDate>
		<dc:creator>Raphaël Lévy</dc:creator>
				<category><![CDATA[PhD]]></category>
		<category><![CDATA[the lab]]></category>
		<category><![CDATA[Chris]]></category>
		<category><![CDATA[viva]]></category>

		<guid isPermaLink="false">http://raphazlab.wordpress.com/?p=690</guid>
		<description><![CDATA[Long overdue post: Chris viva was on the 15th of December. After minor corrections, he will officially be Dr Shaw. Congratulations!<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=raphazlab.wordpress.com&amp;blog=4635881&amp;post=690&amp;subd=raphazlab&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p>Long overdue post: Chris viva was on the 15th of December. After minor corrections, he will officially be Dr Shaw. Congratulations!</p>
<p><a href="http://raphazlab.files.wordpress.com/2012/01/chris-phd.jpg"><img class="alignleft size-full wp-image-691" title="Chris PhD" src="http://raphazlab.files.wordpress.com/2012/01/chris-phd.jpg?w=500" alt=""   /></a></p>
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			<media:title type="html">Chris PhD</media:title>
		</media:content>
	</item>
		<item>
		<title>Research misconduct in the UK</title>
		<link>http://raphazlab.wordpress.com/2012/01/12/research-misconduct-in-the-uk/</link>
		<comments>http://raphazlab.wordpress.com/2012/01/12/research-misconduct-in-the-uk/#comments</comments>
		<pubDate>Thu, 12 Jan 2012 21:22:39 +0000</pubDate>
		<dc:creator>Raphaël Lévy</dc:creator>
				<category><![CDATA[Science and ethics]]></category>

		<guid isPermaLink="false">http://raphazlab.wordpress.com/?p=685</guid>
		<description><![CDATA[Time to act say COPE Chair, Liz Wager, and BMJ editor in chief, Fiona Godlee, who discuss the lack of systems in place to investigate research misconduct in the UK. The editorial is published in the BMJ and is also available here; excerpt: The meeting will hear that research misconduct is alive and well in [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=raphazlab.wordpress.com&amp;blog=4635881&amp;post=685&amp;subd=raphazlab&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p>Time to act say <a title="COPE" href="http://publicationethics.org">COPE</a> Chair, Liz Wager, and BMJ editor in chief, Fiona Godlee, who discuss the lack of systems in place to investigate research misconduct in the UK. The editorial is published in the <a title="BMJ" href="http://www.bmj.com/">BMJ</a> and is also available <a title="Edito" href="http://publicationethics.org/files/BMJ%20editorial_Jan%2012.pdf" target="_blank">here</a>; excerpt:</p>
<blockquote><p>The meeting will hear that research misconduct is alive and well<br />
in the UK even when tightly defined as intentional acts of<br />
falsification and fabrication. It is almost certainly flourishing<br />
when defined more broadly—as some are now arguing it should<br />
be 12—to include a wide range of questionable behaviours that<br />
threaten the integrity of science, including suppression of data<br />
and failure to publish research results.</p></blockquote>
<p>&nbsp;</p>
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		<title>Fmoc-diphenylalanine hydrogels: understanding the variability in reported mechanical properties</title>
		<link>http://raphazlab.wordpress.com/2011/12/05/fmoc-diphenylalanine-hydrogels-understanding-the-variability-in-reported-mechanical-properties/</link>
		<comments>http://raphazlab.wordpress.com/2011/12/05/fmoc-diphenylalanine-hydrogels-understanding-the-variability-in-reported-mechanical-properties/#comments</comments>
		<pubDate>Mon, 05 Dec 2011 16:01:04 +0000</pubDate>
		<dc:creator>Raphaël Lévy</dc:creator>
				<category><![CDATA[New publication]]></category>
		<category><![CDATA[fibres]]></category>
		<category><![CDATA[hydrogels]]></category>
		<category><![CDATA[materials]]></category>

		<guid isPermaLink="false">http://raphazlab.wordpress.com/?p=674</guid>
		<description><![CDATA[That&#8217;s the title of Jaclyn Raeburn&#8217;s article. She is a PhD student in Dave Adams group, and we are delighted to have contributed to this story now published in the journal Soft Matter.<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=raphazlab.wordpress.com&amp;blog=4635881&amp;post=674&amp;subd=raphazlab&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p>That&#8217;s the title of Jaclyn Raeburn&#8217;s article. She is a PhD student in <a title="Dave Adams' group" href="http://www.xaudia.com/dja/dja/Welcome.html" target="_blank">Dave Adams group</a>, and we are delighted to have contributed to this story <a title="Fmoc-hydrogels" href="http://xlink.rsc.org/?doi=C1SM06929B" target="_blank">now published</a> in the journal Soft Matter.</p>
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		<title>Lara to present her results at BIOS SPIE Photonics West</title>
		<link>http://raphazlab.wordpress.com/2011/11/21/lara-to-present-her-results-a/</link>
		<comments>http://raphazlab.wordpress.com/2011/11/21/lara-to-present-her-results-a/#comments</comments>
		<pubDate>Mon, 21 Nov 2011 15:09:15 +0000</pubDate>
		<dc:creator>Raphaël Lévy</dc:creator>
				<category><![CDATA[Conference]]></category>
		<category><![CDATA[Invited lecture]]></category>
		<category><![CDATA[Bionano meeting]]></category>
		<category><![CDATA[international]]></category>
		<category><![CDATA[intracellular delivery]]></category>
		<category><![CDATA[nanoparticle]]></category>
		<category><![CDATA[Photothermal]]></category>
		<category><![CDATA[SPIONs]]></category>

		<guid isPermaLink="false">http://raphazlab.wordpress.com/?p=661</guid>
		<description><![CDATA[Colloidal Nanocrystals for Biomedical Applications, San Francisco, 21 &#8211; 26 January 2012<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=raphazlab.wordpress.com&amp;blog=4635881&amp;post=661&amp;subd=raphazlab&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p><a title="BIOS" href="http://spie.org/app/program/index.cfm?fuseaction=conferencedetail&amp;conference_id=961689&amp;event_id=896186" target="_blank">Colloidal Nanocrystals for Biomedical Applications</a>, San Francisco, 21 &#8211; 26 January 2012</p>
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		<title>Shimon Weiss in Liverpool</title>
		<link>http://raphazlab.wordpress.com/2011/11/18/shimon-weiss-in-liverpool/</link>
		<comments>http://raphazlab.wordpress.com/2011/11/18/shimon-weiss-in-liverpool/#comments</comments>
		<pubDate>Fri, 18 Nov 2011 09:56:25 +0000</pubDate>
		<dc:creator>Raphaël Lévy</dc:creator>
				<category><![CDATA[Leica lectures]]></category>
		<category><![CDATA[Single molecule]]></category>
		<category><![CDATA[cells]]></category>
		<category><![CDATA[fluorescence]]></category>
		<category><![CDATA[nanoparticle]]></category>
		<category><![CDATA[single molecule]]></category>

		<guid isPermaLink="false">http://raphazlab.wordpress.com/?p=629</guid>
		<description><![CDATA[The Leica lectures bring regularly excellent speakers to Liverpool. Not to be missed, on the 6th of December, 5:00pm, Liverpool University, Lecture Theatre 2, Life Sciences Building: Multiscale, Superresolved, Ultrasensitive Optical Molecular Imaging by Professor Shimon Weiss, UCLA<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=raphazlab.wordpress.com&amp;blog=4635881&amp;post=629&amp;subd=raphazlab&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p><a title="Leica lectures" href="http://www.leica-microsystems.com/science-lab/events/event-details/?tx_cal_controller[view]=event&amp;tx_cal_controller[type]=tx_cal_phpicalendar&amp;tx_cal_controller[uid]=1440&amp;tx_cal_controller[lastview]=view-list|page_id-2678&amp;tx_cal_controller[year]=2011&amp;tx_cal_controller[month]=12&amp;tx_cal_controller[day]=05&amp;cHash=32f526afbb5f2aa396cd460b9fbe279a" target="_blank">The Leica lectures</a> bring regularly excellent speakers to Liverpool. Not to be missed, on the 6th of December, 5:00pm, Liverpool University, Lecture Theatre 2, Life Sciences Building:</p>
<blockquote>
<h3>Multiscale, Superresolved, Ultrasensitive Optical Molecular Imaging</h3>
<p>by Professor <a href="http://www.openwetware.org/wiki/Weiss_Lab" target="_blank">Shimon Weiss</a>, UCLA</p></blockquote>
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		<title>Feeding students</title>
		<link>http://raphazlab.wordpress.com/2011/10/29/feeding-students/</link>
		<comments>http://raphazlab.wordpress.com/2011/10/29/feeding-students/#comments</comments>
		<pubDate>Sat, 29 Oct 2011 22:18:31 +0000</pubDate>
		<dc:creator>Raphaël Lévy</dc:creator>
				<category><![CDATA[Teaching]]></category>
		<category><![CDATA[Biol 135]]></category>

		<guid isPermaLink="false">http://raphazlab.wordpress.com/?p=626</guid>
		<description><![CDATA[That&#8217;s it, I am no more a BBSRC Fellow, instead, call me a Lecturer. In addition to research, I have to feed knowledge to hungry students: with this change of title comes an increase in the amount of teaching I have the pleasure to do (and the students have the pleasure to endure). In Biol [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=raphazlab.wordpress.com&amp;blog=4635881&amp;post=626&amp;subd=raphazlab&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p>That&#8217;s it, I am no more a BBSRC Fellow, instead, call me a Lecturer. In addition to research, I have to feed knowledge to hungry students: with this change of title comes an increase in the amount of teaching I have the pleasure to do (and the students have the pleasure to endure).</p>
<p>In <a title="QB1" href="http://www.liv.ac.uk/info/portal/pls/portal30/tulwwwmerge.mergepage?p_template=m_bs&amp;p_tulipproc=moddets&amp;p_params=%3Fp_module_id%3D38795">Biol 135</a>, the lecture on linear function (delivered to a few hundreds students in a big lecture theatre) was constructed around the example of apes climbing 15 metres of a tree for each bananas (a great idea; not mine). On the way to the lecture, I stopped to buy a couple of bananas and finished the lecture with a challenge about the definition of functions. The prize for the winners were, of course, the bananas.</p>
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		<title>Je sers la science et c&#8217;est ma joie</title>
		<link>http://raphazlab.wordpress.com/2011/10/20/je-sers-la-science-et-cest-ma-joie/</link>
		<comments>http://raphazlab.wordpress.com/2011/10/20/je-sers-la-science-et-cest-ma-joie/#comments</comments>
		<pubDate>Thu, 20 Oct 2011 17:34:03 +0000</pubDate>
		<dc:creator>Raphaël Lévy</dc:creator>
				<category><![CDATA[Art]]></category>
		<category><![CDATA[Public understanding of science]]></category>
		<category><![CDATA[Social and economic aspects of nanotechnology]]></category>
		<category><![CDATA[Leonard]]></category>
		<category><![CDATA[Paintings]]></category>

		<guid isPermaLink="false">http://raphazlab.wordpress.com/?p=613</guid>
		<description><![CDATA[This is Leonard&#8217;s disciple motto, and it is also the title of this major piece of art (designed and painted by Paul Picard, my grand-dad) which has now found its home in my office. Challenge: how many of the characters on the frame can you identify (answer in the comments box please)? A higher resolution [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=raphazlab.wordpress.com&amp;blog=4635881&amp;post=613&amp;subd=raphazlab&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p>This is <a href="http://en.wikipedia.org/wiki/L%C3%A9onard_%28comics%29">Leonard&#8217;s disciple</a> motto, and it is also the title of this major piece of art (designed and painted by Paul Picard, my grand-dad) which has now found its home in my office.</p>
<p>Challenge: how many of the characters on the frame can you identify (answer in the comments box please)?</p>
<p>A higher resolution version <a title="Je sers la science et c'est ma joie" href="http://raphazlab.files.wordpress.com/2011/10/je-sers-la-science.jpg" target="_blank">here</a>.</p>
<p><a href="http://raphazlab.files.wordpress.com/2011/10/je-sers-la-science-reduced.jpg"><img class="alignleft size-full wp-image-614" title="Je sers la science et c'est ma joie" src="http://raphazlab.files.wordpress.com/2011/10/je-sers-la-science-reduced.jpg?w=500&#038;h=610" alt="" width="500" height="610" /></a></p>
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		<slash:comments>3</slash:comments>
	
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		<media:content url="http://raphazlab.files.wordpress.com/2011/10/je-sers-la-science-reduced.jpg" medium="image">
			<media:title type="html">Je sers la science et c&#039;est ma joie</media:title>
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		<title>The case of Dr Hicheur</title>
		<link>http://raphazlab.wordpress.com/2011/10/13/the-case-of-dr-hicheur/</link>
		<comments>http://raphazlab.wordpress.com/2011/10/13/the-case-of-dr-hicheur/#comments</comments>
		<pubDate>Thu, 13 Oct 2011 21:00:08 +0000</pubDate>
		<dc:creator>Raphaël Lévy</dc:creator>
				<category><![CDATA[Social and economics aspects of science]]></category>
		<category><![CDATA[Hicheur]]></category>

		<guid isPermaLink="false">http://raphazlab.wordpress.com/?p=609</guid>
		<description><![CDATA[Nature has an editorial on the case of this French-Algerian scientist who has been in jail for nearly two years in France under charges of terrorism. Hicheur&#8217;s work at CERN, Europe&#8217;s premier high-energy physics laboratory near Geneva in Switzerland, certainly made for some good headlines — “Nuclear terror suspect is top physicist”, for example. And, [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=raphazlab.wordpress.com&amp;blog=4635881&amp;post=609&amp;subd=raphazlab&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p>Nature has an editorial on the case of this French-Algerian scientist who has been in jail for nearly two years in France under charges of terrorism.</p>
<blockquote><p>Hicheur&#8217;s work at CERN, Europe&#8217;s premier high-energy physics laboratory near Geneva in Switzerland, certainly made for some good headlines — “Nuclear terror suspect is top physicist”, for example. And, at this stage, <em>Nature</em> is in no position to judge his innocence or guilt, which is a question for the French judicial system.</p>
<p>Nonetheless, Hicheur&#8217;s case deserves attention because to have held him in custody for so long, although legal under France&#8217;s tough anti-terror laws, seems a clear abuse of human rights.</p></blockquote>
<p>Read it all <a title="Nature Editorial Hicheur" href="http://www.nature.com/nature/journal/v478/n7368/full/478155a.html" target="_blank">here</a>.</p>
<p>There is also an international <a href="http://soutien.hicheur.pagesperso-orange.fr/index_EN.html" target="_blank">support committee </a>and a <a href="http://www.mesopinions.com/Liberte-pour-Adlene-Hicheur--590-jours-de-detention-provisoire--ne-l-oublions-pas-petition-petitions-d16f6e3fed1c169ca205b95530a4bd90.html" target="_blank">petition</a> (in French, letter to the Justice minister asking for his freedom until trial takes place).</p>
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